Protects epidermal stem cells from UV stress
PhytoCellTec™ Alp Rose preserves stem cells' vitality even under UV radiation.

Ski holiday study
The effect of PhytoCellTec™ Alp Rose in extreme environmental conditions over 2 weeks. Result: PhytoCellTec™ Alp Rose prevented skin dehydration by 39% water loss.

Ski holiday study
Visible skin wrinkles and redness/irritation were reduced by 45% and 54% respectively.

PhytoCellTec™ Alp Rose

PhytoCellTec™ Alp Rose is a cosmetic ingredient based on stem cells of alpine rose leaves.

The Alpine rose
The alpine rose is a typical Swiss flowering plant from the Alps. It has bright pink blossoms and grows at altitudes up to 3200 m. Its evergreen leaves are especially resistant to high UV radiation and extreme dryness and cold. The sturdy leaves are a shiny green, even once the snow has melted in the spring. This phenomenon is due to the presence of a special protection protein called dehydrin in the leaves of the alpine rose.

Plant stem cells for skin stem cells
For years researchers at Mibelle Biochemistry have investigated the compounds of the alpine rose and its special protective substances, in particular, the water-retaining dehydrin. The innovative PhytoCellTec™ technology has been used to develop a formula from the leaves' stem cells that treats dry and stressed skin and has been proven to protect skin cells: PhytoCellTec™ Alp Rose.

The effect
Mibelle Biochemistry was able to show in extensive studies that PhytoCellTec™ Alp Rose promotes the vitality and longevity of skin stem cells. It strengthens the skin barrier, providing better protection to the skin against climate-induced stress.

Summary
The effect of PhytoCellTec™ Alp Rose combines two important approaches. Using plant stem cells delays skin aging by protecting vital skin stem cells, keeping the skin looking youthful longer, and giving it a better and more vital appearance. At the same time, PhytoCellTec™ Alp Rose protects the skin using special protective ingredients from this extremely resistant alpine plant.

Protects epidermal stem cells from UV stress
Cultures of epidermal stem cells were treated with PhytoCellTec™ Alp Rose, while others were left untreated. The cultures were then exposed to UVA and UVB rays. The colony-forming efficiency (CFE) of the stem cells was then measured. The results showed that UV radiation strongly reduces the cells' colony-forming efficiency. Treatment with PhytoCellTec™ Alp Rose increased the stem cells' colony-forming efficiency (vitality) and provided significant protection against UV rays. (see chart)

Ski holiday study
Twenty-two subjects were treated with an SPF 30 sunscreen formula during their ski holidays (1 week in March, Alps) to test the effect of PhytoCellTec™ Alp Rose in extreme environmental conditions. Sunscreen without the active ingredient was applied to one side of a subject's face, while the other side was treated with sunscreen containing the active ingredient PhytoCellTec™ Alp Rose. The loss of skin moisture in the face was then measured after another week of treatment at home. The results showed that water loss was reduced by 39% after 2 weeks’ treatment with PhytoCellTec™ Alp Rose. This indicates that PhytoCellTec™ Alp Rose strengthens the skin barrier and makes it more resistant to environmental stresses such as UV, wind, cold temperatures and dryness. (see chart)